THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
(LO 4257) FEBRUARY 2019 Sub. Code: 4257
B.PHARM. DEGREE EXAMINATION
SECOND YEAR
PAPER II PHARMACEUTICAL ANALYSIS PHYSICAL CHEMISTRY
Q.P. Code: 564257
Time: Three hours Maximum: 100 Marks
Answer All Questions
SECTION-A
(PHARMACEUTICAL ANALYSIS)
I. Elaborate on: x 20 20)
1. a Explain the calibration of volumetric Apparatus.
Explain oxygen flask combustion method for the determination of Sulpher.
II. Write notes on: x 5 20)
1. Write a note on Significant figure.
2. Preparation standardization of Perchloric acid.
3. PM Indicators.
4. Organic Precipitants in gravimetry.
III. Short answers on: x 2 10)
1. Accuracy.
2. Saponification value.
3. Iodometry.
4. Argentimetry.
5. Co-precipitation.
SECTION-B
(PHYSICAL CHEMISTRY)
I. Elaborate on: x 20 20)
1. Explain Hess's law of constant heat of summation.
Write in detail about theories of order of Reaction.
II. Write notes on: x 5 20)
1. Explain about Bomb Calorimeter.
2. Write a note on Partition coefficient with limitations.
3. Define solutions with its types.
4. State and explain Joule Thomson Effect.
III. Short answers on: x 2 10)
1. Enzyme Catalyst.
2. Eutectic Point.
3. Entropy.
4. Adsorption isotherm.
5. Refractive index.