THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LN 804] AUGUST 2018 Sub. Code: 3804
PHARM. D DEGREE EXAMINATION
(2009-2010 Regulation)
FIRST YEAR
PAPER IV PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code 383804
Time Three hours Maximum 70 Marks
I. Elaborate on: x 10 40)
1. Define elimination reaction. Explain about its Kinetic, mechanism and isotopic
effect of E1and E2 reactions.
2. Write a note on Markownikoff's rule and Peroxide effect.
3. Explain the following reactions:
Aldol condensation. ii) Michael addition.
4. Explain Bayer's Strain Theory and discuss its limitations.
II. Write notes on: x 5 30)
1. Write a note on activating and deactivating and M directing groups.
2. Explain Cannizaro reaction.
3. Add a note on Structural Isomerism.
4. Add a note on Free Radical substitution reaction of alkanes.
5. Preparation, test for purity, assay and uses of Vanillin.
6. What is dipole moment? Explain with suitable example.