Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
M.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: MPL201T Date: 15/11/2018
Subject Name: Advanced Pharmacology II
Time :02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Describe uses and adverse effects of corticosteroids
06

Justify use of folinic acid in the treatment of methotrexate toxicity.
05

Classify Penicillins. Describe the Pharmacology of Ampicillin.
05
Q.2

Enlist various hormone antagonists used in cancer chemotherapy. Write a note on tamoxifen.
06

Write a note on oral contraceptives
05

Write a short note on imidazole derivatives used in treatment of amoebiasis.
05
Q.3

Write in detail about mechanism of action, therapeutic uses and adverse effects of Tetracycline.
06

Write a note on Prokinetics agents
05

Write a note on ketoconazole.
05
Q.4

Write a note on proton pump inhibiters
06

Justify following
Mesna is given with cyclophosphamide.
Pyridoxine is given with isoniazide.
05

Explain in brief about pharmacotherapy of tuberculosis.
05
Q.5

Write a note on recent Advances in treatment of Alzheimer's disease.
06

Classify antimalarials. Write a note on artemisinin.
05

Write a note on antidiarrheal agents
05
Q. 6

Write a note on recent Advances in treatment of Parkinson's disease.
06

What are HAART regimens? Write a note on zidovudine.
05

Write a note on anti asthamatic drugs
05
Q.7

Write a note on recent Advances in treatment of Diabetes mellitus.
06

Enlist immunosuppressants. Write a note on cyclosporin.
05

Explain mechanism of action, therapeutic uses and adverse effects of aminoglycosides.
05