Exam Details

Subject advanced organic chemistry -i
Paper
Exam / Course mca
Department
Organization Gujarat Technological University
Position
Exam Date January, 2019
City, State gujarat, ahmedabad


Question Paper

Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
M.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: MPC102T Date: 03/01/2019
Subject Name: Advanced Organic Chemistry
Time :10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt Any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Give the reaction mechanism of vilsmeyer-Hack reaction with suitable example
06

Explain what is Walden inversion and write the differences of SN1 and SN2 reactions
05

Write a note on Sharpless asymmetric epoxidation and its synthetic application
05
Q.2

Wrirte in detail E2 reaction and describe Hoffman and Saytzeff's rule with suitablen examples.
06

Write in detail the synthetic route of Trimethoprim and give its uses
05

Write the mechanism and synthetic application of Michael addition reaction
05
Q.3

Write a note on formation, stability and synthetic application of carbanions
06

Write a note on functional group interconversion and C-C disconnections with suitable examples.
05

Give the mechanism of Knor pyrazole synthesis and its application in drug synthesis
05
Q.4

Write the mechanism and application of Troube purine synthesis
06

Give different synthon approach strategies for synthesis of five and six membered rings.
05

Describe in detail the role of carbamates and amides as protecting groups with suitable examples
05
Q.5

Write the chemistry of Wilkinson reagent and give its applications
06

Write the synthesis of chloroquine and its uses
05

Write a note on Ullmann coupling reactions and give its synthetic application
05
Q. 6

Write a note on carboxyl group protection with examples using esters, amides and hydrazides.
06

Give the mechanism and one synthetic application of Doebner-Miller reaction
05

Write a note on Baeyer-Villiger oxidation and give its synthetic application
05
Q.7

Describe the basic principles of retrosynthesis with suitable examples
06

Explain the formation and stability of carbenes and nitrenes with suitable examples
05

Write the mechanism and application of Shapiro Suzuki reaction
05



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  • advance database management system
  • advanced biopharmaceutics & pharmacokinetics
  • advanced medicinal chemistry
  • advanced networking (an)
  • advanced organic chemistry -i
  • advanced pharmaceutical analysis
  • advanced pharmacognosy-1
  • advanced python
  • android programming
  • artificial intelligence (ai)
  • basic computer science-1(applications of data structures and applications of sql)
  • basic computer science-2(applications of operating systems and applications of systems software)
  • basic computer science-3(computer networking)
  • basic computer science-4(software engineering)
  • basic mathematics
  • basic statistics
  • big data analytics (bda)
  • big data tools (bdt)
  • chemistry of natural products
  • cloud computing (cc)
  • communications skills (cs)
  • computer aided drug delivery system
  • computer graphics (cg)
  • computer-oriented numerical methods (conm)
  • cyber security & forensics (csf)
  • data analytics with r
  • data mining
  • data structures (ds)
  • data visualization (dv)
  • data warehousing
  • data warehousing & data mining
  • database administration
  • database management system (dbms)
  • design & analysis of algorithms(daa)
  • digital technology trends ( dtt)
  • discrete mathematics for computer science (dmcs)
  • distributed computing (dc1)
  • drug delivery system
  • dynamic html
  • enterprise resource planning (erp)
  • food analysis
  • function programming with java
  • fundamentals of computer organization (fco)
  • fundamentals of java programming
  • fundamentals of networking
  • fundamentals of programming (fop)
  • geographical information system
  • image processing
  • industrial pharmacognostical technology
  • information retrieving (ir)
  • information security
  • java web technologies (jwt)
  • language processing (lp)
  • machine learning (ml)
  • management information systems (mis)
  • mobile computing
  • molecular pharmaceutics(nano tech and targeted dds)
  • network security
  • object-oriented programming concepts & programmingoocp)
  • object-oriented unified modelling
  • operating systems
  • operation research
  • operations research (or)
  • pharmaceutical validation
  • phytochemistry
  • procedure programming in sql
  • programming skills-i (ps-i-fop)
  • programming skills-ii (ps-oocp)
  • programming with c++
  • programming with java
  • programming with linux, apache,mysql, and php (lamp)
  • programming with python
  • search engine techniques (set)
  • soft computing
  • software development for embedded systems
  • software engineering
  • software lab (dbms: sql & pl/sql)
  • software project in c (sp-c)
  • software project in c++ (sp-cpp)
  • software quality and assurance (sqa)
  • statistical methods
  • structured & object oriented analysis& design methodology
  • system software
  • virtualization and application of cloud
  • web commerce (wc)
  • web data management (wdm)
  • web searching technology and search engine optimization
  • web technology & application development
  • wireless communication & mobile computing (wcmc)
  • wireless sensor network (wsn)