Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
PHARM.D YEAR EXAMINATION -WINTER 2018
Subject Code: 818805 Date: 30/11/2018
Subject Name: Pharmaceutical Inorganic Chemistry
Time: 10.30 A.M. TO 1.30 P.M. Total Marks: 70
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Define error. Explain types of error and its minimization.
06

Write a note on acidifiers
04

Write brief note on construction and working of galvanic cell.
04
Q.2

Enlist the sources of the impurities in Pharmaceuticals and discuss any two source of impurity.
06

Write a note on role of Oxygen
04

Define precipitation titration. Discuss ideal requirement of a reaction to be used in precipitation titration.
04
Q.3

What is ligand? Classify ligand. Write note on Chelating agents.
06

Explain leveling effect and differentiating effect in Non aqueous titration.
04

Write a note on Anti-caries agents
04
Q.4

Give preparation and properties of the following:
Aluminium hydroxide gel ii) Precipitated Chalk iii) Baking soda
06

Discuss theory of solubility product constant (Ksp).
04

Explain Importance of Digestion and Washing in gravimetry.
04
Q.5

What is radioactivity? Discuss storage condition of radiopharmaceuticals.
ii) Write a note on Geiger-Muller Counter
06

Write a note on sclerosing agents.
04

Explain in detail redox titration curve.
04
Q. 6

What is buffer solution? Derive Henderson-hesselbatch equation for finding pH of buffer solution.
06

Discuss in detail ORS
04

Define following terms:
Preservatives ii) Filter aids iii) Cathartics iv) Argentometric Titration
04
Q.7

Discuss neutralization curve of weak base vs. strong acid titration with example.
06

What is antacid? Give ideal requirements of antacid.
04

Discuss the pharmaceutical importance of Iron and haematinics.
04