Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
Pharm D 1st Year • EXAMINATION SUMMER 2018
Subject Code:818803 Date: 23/05/2018
Subject Name: Medicinal Biochemistry
Time:10:30AM TO 01:30PM Total Marks: 70
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Discuss at length the process of beta oxidation of fatty acids with energetics
06

Discuss about defective metabolism of lipids
04

Explain ketone bodies formation and their utilization
04
Q.2

Classify proteins according to their biological functions. Write about kwashiorkor and marasmus.
06

Discuss urea cycle
04

Discuss about abnormal metabolism of proteins
04
Q.3

Explain citric acid cycle with its energetic
06

Define coenzymes. Explain their biochemical role and deficiency diseases
04

Discuss specificity of enzymes
04
Q.4

Explain cori's cycle Glycogen storage disorders
06

Describe the components of electron transfer chain and discuss the oxidation of NADH
04

Discuss about uncouplers as inhibitors of oxidative phosphorylation
04
Q.5

Describe the hexose monophosphate shunt and add a note on its significance
06

Write a note on distribution of water and water balance in humans
04

Write in brief about the different laboratory investigations employed to assess liver functions
04
Q. 6

Write note on energy rich compounds
06

Write briefly on the renal function tests
04

Discuss about role of clinical chemistry laboratory composition and functions of lipoproteins
04
Q.7

Write note on damage and repair of DNA
06

Discuss about Gene expression in eukaryotes
04

Write note on RIA
04