Exam Details

Subject pharmaceutical organic chemistry
Paper
Exam / Course b.pharm
Department
Organization Gujarat Technological University
Position
Exam Date May, 2018
City, State gujarat, ahmedabad


Question Paper

Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
Pharm D 1st Year • EXAMINATION SUMMER 2018
Subject Code: 818804 Date: 25/05/2018
Subject Name: Pharmaceutical Organic Chemistry
Time: 10:30 AM TO 1:30 PM Total Marks: 70
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Classify Intramolecular Forces and Explain Bond dissociation Energy.
06

Explain Following Terms
1. Heterolysis
2. Homolysis
3. Dipole-Dipole interaction
4.Polarity of bond
04

Explain the reactivity and stability of free radical.
04
Q.2

Discuss the mechanism and stereochemistry of SN1 AND SN2 reaction.
06

Write a note on Carbocations with mechanism.
04

Write a note on: Methods of preparation of cycloalkanes.
04
Q.3

Explain the influence of activating and deactivating groups on the electrophillic substitution of benzene.
06

Explain oxidation-reduction reaction with examples.
04

Give chemical structure and IUPAC name of following
2,2,4-Trimethylpentane, 1-methoxy-2-propanol,2-Nitrophenol ,Vinyl bromide
04
Q.4

Give the preparation, test of purity, assay and medicinal use of
1. chlorbutol
2. Sodium lauryl sulphate.
06

Differentiate E1 and E2 reaction.
04

Explain the halohydrin formation.
04
Q.5

Explain the following:
1.aldol condensation
2.Sandmeyer's reaction
06

Explain the cycloaddition reaction.
04

Explain the resonance and hyper-conjugation.
04
Q. 6

Comment on the following
1. Meta nitro benzoic acid is more acidic than Para nitro benzoic Acid
2. Pyridine is aromatic
3. All Lowrie-Bronsted acids and bases can be Lewis acids and bases
but all Lewis acids and bases cannot be Lowrie-Bronsted acids and bases
06

Write detail note on Nucleophilic substitution bimolecular.
04

Explain Isomerism in organic compound
04
Q.7

Explain the Perkin condensation and Kolbe reaction.
06

Write free radical halogenations reaction of alkenes.
04

Write a note on Markownikov's rule in detail.
04



Subjects

  • agronomy and forestry of medicinal plants
  • anatomy physiology & health education -ii
  • anatomy, physiology and health education (aphe)
  • applied mathematics (biostatistics)
  • basic computer applications
  • basic concepts of pharmacology and clinical pharmacy practice
  • basics of computer applications
  • bioavailability & therapeutic drug monitoring
  • bioavailability and therapeutic drug monitoring
  • biochemistry
  • clinical pharmacy ii
  • clinical pharmacy-i
  • commerce of herbs and phytoconstitutents
  • computer applications in drug discovery
  • current advances in novel drug delivery systems
  • cyber security
  • disaster management
  • dispensing pharmacy i
  • dispensing pharmacy i and drug store management
  • dispensing pharmacy ii and pharma industrial management
  • dosage form design –i
  • dosage form design- i
  • dosage form design- ii
  • dosage form design-i
  • dosage form design-ii
  • drug approval process
  • environmental studies
  • environmental toxicology and green audit
  • food analysis
  • forensic pharmacy
  • forensic pharmacy-i
  • genetic engineering and gene therapy
  • green chemistry
  • health education and community health
  • herbal cosmetics
  • hospital and community pharmacy
  • hospital management and medical tourism
  • hospital pharmacy, community pharmacy & forensic pharmacy
  • hospital pharmacy, community pharmacy and dispensing pharmacy-ii
  • human anatomy physiology
  • human anatomy physiology and health education-ii
  • human anatomy physiology-ii
  • human anatomy, physiology and health education - i
  • innovations in conventional drug delivery system
  • instrumental and process validation
  • intellectual property rights and patents
  • medical writing and coding
  • medicinal biochemistry
  • nutraceuticals
  • pathophysiology
  • pharmaceutical analysis ii
  • pharmaceutical analysis iii
  • pharmaceutical analysis iv
  • pharmaceutical analysis-i
  • pharmaceutical analysis-ii
  • pharmaceutical analysis-iv
  • pharmaceutical chemistry – ii
  • pharmaceutical chemistry – vi (organic chemistry – ii)
  • pharmaceutical chemistry –viii (medicinal chemistry - ii)
  • pharmaceutical chemistry iii
  • pharmaceutical chemistry iv
  • pharmaceutical chemistry vii
  • pharmaceutical chemistry-i
  • pharmaceutical chemistry-i (inorganic chemistry)
  • pharmaceutical chemistry-ii (physical chemistry)
  • pharmaceutical chemistry-iii (biochemistry – i)
  • pharmaceutical chemistry-iv (organic chemistry-i)
  • pharmaceutical chemistry-ix (medicinal chemistry-iii)
  • pharmaceutical chemistry-v
  • pharmaceutical chemistry-v (biochemistry-ii)
  • pharmaceutical chemistry-vi (medicinal)
  • pharmaceutical chemistry-vii
  • pharmaceutical chemistry-viii
  • pharmaceutical chemistry-x
  • pharmaceutical chemistry-x (medicinal chemistry-iii)
  • pharmaceutical engineering
  • pharmaceutical engineering-ii
  • pharmaceutical inorganic chemistry
  • pharmaceutical marketing management
  • pharmaceutical microbiology - i
  • pharmaceutical microbiology & biotechnology i
  • pharmaceutical microbiology &biotechnology- ii
  • pharmaceutical microbiology and biotechnology - ii
  • pharmaceutical organic chemistry
  • pharmaceutical technology - i
  • pharmaceutical technology – i
  • pharmaceutical technology- ii
  • pharmaceutical technology-i
  • pharmaceutical technology-ii
  • pharmaceutics-i
  • pharmaceutics-ii
  • pharmaceutivcal chemistry ix
  • pharmacognosy iii
  • pharmacognosy iv
  • pharmacognosy vi
  • pharmacognosy vii
  • pharmacognosy vii (herbal formulations & complimentary therapies)
  • pharmacognosy-i
  • pharmacognosy-ii
  • pharmacognosy-iii
  • pharmacognosy-iv
  • pharmacognosy-v
  • pharmacognosy-v (plant bio technology)
  • pharmacognosy-vi
  • pharmacology -iii
  • pharmacology & pharmacotherapeutics-ii
  • pharmacology and pharmacotherapeutics - i
  • pharmacology and pharmacotherapeutics - iii
  • pharmacology and pharmacotherapeutics-iv
  • pharmacology-i
  • pharmacology-ii
  • pharmacovigilance
  • pharmacy practice
  • physical pharmaceutics-ii
  • physical pharmacy
  • quality by design (qbd) and process analytical technology (pat)
  • regulatory aspects of food and neutraceuticals
  • remedial mathematics
  • unit operation - i
  • unit operation - ii