FACULTY OF PHARMACY
B. Pharmacy 2/4 II-Semester (Non-CBCS) (Backlog) Examination, December 2018
Subject Pharmaceutical Biochemistry
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Explain with a neat diagram biochemical organization of cell.
Discuss the various transport mechanisms across the cell membrane.
OR
Write the concept of free energy.
Describe the method of production of ATP and its biological significance.
2 Explain the direct oxidative pathway of carbohydrate.
Discuss the sequence of reactions involved in Glycolysis.
OR
Discuss the pathway of Glucogenesis. Mention the key enzymes responsible.
Write the reactions of Krebs cycle.
3 Discuss the various steps involved in the biosynthesis of cholesterol.
What is Enumerate the pathways of -oxidation.
OR
Write briefly on Classification of enzymes Factors Influencing enzyme
activity.
Write notes on
Activation and deactivation of enzymes
Co-enzymes
4 Describe the Trans-amination.
Write briefly on physical and chemical mutagenesis.
OR
Explain the various DNA repair mechanism.
Write briefly on inborn error in metabolism.
5 Describe the principles and methods involved in the quantitative analysis
of SGPT and SGOT.
Write the principles and methods involved in the qualitative analysis of urinary
Bile salts and Bile pigments.
OR
Write the principle and procedure involved in the estimation of serum Glucose.
Write its biological importance.
Describe the principles and methods involved in the quantitative analysis
of Creatinine in urine.
Give the qualitative test for the identification of abnormal constituents of
urine.