BIO/VI/11 Student's Copy
2 0 1 8
6th Semester
BIOTECHNOLOGY
Paper BT-XI
Immunology
Full Marks 55
Time 2½ hours
PART A—OBJECTIVE
Marks 20
The figures in the margin indicate full marks for the questions
SECTION—A
Marks 5
Tick the correct answer in the brackets provided 1×5=5
1. Cytokine which induces the terminal development of erythrocytes and
regulates the production of red blood cell is
colony stimulating factor
erythropoietin
interleukin
interferon
/527 1 Contd.
2. Two antibodies that have the same antigenic recognition sequences are
called as
allotype
isotype
idiotype
None of the above
3. Which of the following substances will not stimulate an immune response
unless they are bound to a larger molecule?
Antigen
Virus
Hapten
Epitope
4. An inflammation of the spleen and dark-coloured urine indicates
autoimmuneanaemia
Goodpasture's syndrome
myasthenia gravis
Graves' disease
5. The most widely used serological test for antigen or antibody detection is
flow cytometry
ELISA
RIA
immunoprecipitation
BIO/VI/11/527 2 Contd.
SECTION—B
Marks 15
Write notes on the following 3×5=15
1. Thymus
2. Isotypes
3. Adjuvants
4. Tolerance
5. Competitive ELISA
PART B—DESCRIPTIVE
Marks 35
The figures in the margin indicate full marks for the questions
1. Write a note on the cells of the immune system. 7
OR
Elaborate on the developmental process of B-lymphocytes. 7
2. Describe the basic structure and general functions of antibodies. 7
OR
Write a note on the biological activities of different classes of
immunoglobulins. 7
3. What is an antigen-antibody interaction? Write a note on the properties
of antigen-antibody interaction and the types of antigen-antibody
interaction.
OR
What are cytokine receptors? Write a note on the types and structures
of various classes of cytokine receptors.
BIO/VI/11/527 3 Contd.
4. What are HIV-1 and HIV-2? Write a note on how retrovirus HIV-1
infection can result in AIDS.
OR
Write notes on the following 3½+3½=7
Goodpasture's syndrome
Insulin-dependent diabetes mellitus
5. Give a detailed account of the steps involved in Western blotting. Write
a note on the applications of Western blotting.
OR
Write notes on the following 3½+3½=7
Immunoprecipitation
Immunodiffusion