BIO/VI/10 Student's Copy
2 0 1 8
6th Semester
BIOTECHNOLOGY
Paper BT-X
Animal Biotechnology
Full Marks 55
Time 2½ hours
PART A—OBJECTIVE
Marks 20
The figures in the margin indicate full marks for the questions
SECTION—A
Marks 5
Tick the correct answer in the brackets provided 1×5=5
1. The most commonly used polypeptide to coat the surface of a tissue
culture flask is
L-glutamine
a poly-L-lysine
b poly-arginine
None of the above
/526 1 Contd.
2. Which of the following parameters is not considered for the maintenance of
cell culture?
Sub-culture
Replacement of medium
Size of the incubator
Cell morphology
3. The optimal target for embryo placement is known as
maximal implantation potential point
optimum placement point
maximal placement point
optimum implantation potential point
4. The first recombinant human therapeutic protein produced in the milk of
transgenic dairy animals is
kanuma
herceptin
insulin
ATryn
5. Genetic testing of hereditary breast cancer can be detected by alterations
in
BRCA
RET
RB1
None of the above
BIO/VI/10/526 2 Contd.
SECTION—B
Marks 15
Write short notes on the following 3×5=15
1. Growth of cells in culture
2. Cell viability
3. Embryo transfer
4. Herceptin
5. Carrier testing
PART B—DESCRIPTIVE
Marks 35
The figures in the margin indicate full marks for the questions
1. Write a note on cell adhesion molecules. 7
OR
Explain briefly the advantages and applications of cell-culture technology. 7
2. Describe the basic components of cell-culture media and their functions. 7
OR
Write a note on cell counting. 7
3. Elaborate on the different applications of transgenic animals. 7
OR
Write a note on embryonic stem cell technology. 7
BIO/VI/10/526 3 Contd.
4. Write a note on the classification of the US Food and Drug Administration
approved therapeutic proteins. 7
OR
Define molecular pharming. Write a note on proteins used for therapeutic
purpose.
5. Explain how variations in the phase I drug metabolizing enzymes impact
drug metabolism in human beings. 7
OR
Write a note on the applications of pharmacogenomics. 7