FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
RADIOTHERAPY
PAPER III
RTH/D/16/41/III
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Name four situations which require modification of doses
of anti-neoplastic chemotherapy.
Indications, mechanism of action side affects of:
Carboplatin
ii) Sorafenib

2. What is EGFR?
Name the malignancies that are associated with the overexpression
of EGFR.
Explain the role of EGFR targeting in three common
cancers.

3. Name the tumours arising from metaphysis and diaphysis.
Role of the following imaging in Ewing's sarcoma:
Plain X-ray,
ii) MRI scan
iii) PET-CT scan
Immunohistochemistry tests in histopathologic diagnosis
of Ewing's sarcoma.

4. Name the features associated with a known genetic
predisposition to breast carcinoma.
Enumerate the components of risk/benefit assessment
and counseling in breast cancer risk reduction.
Define cancer related fatigue, its evaluation and
management.

5. What are the viral infections associated with CNS
lymphoma?
Staging work up of CNS lymphoma
Evidence for multimodality treatment and its benefit over
radiotherapy alone.

P.T.O.
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
RADIOTHERAPY
PAPER III
6. What are the non-malignant intracranial lesions treated
with radiotherapy?
Radiotherapy technique and dose of thyroid
ophthalmopathy.
5+5
7. A 50 year old lady has a newly diagnosed esophageal
cancer extending from 30 to 35cm (GE junction at 40
cm).What is the role of endoscopic ultrasound and PETCT
Scan in this patient?
Treatment algorithm in the management of the patient.
4+6
8. Transarterial chemo-embolisation: Selection criteria,
indications, contraindications side effects.
2.5x4
9. Role of radiotherapy in small cell carcinoma lung,
Technique of radiotherapy and doses in small cell
carcinoma lung, and
Tolerance doses of organs at risk.

10. Partial breast irradiation: Rationale, Techniques results.
Molecular and genetic characteristics of Glioblastoma
Multiforme with regards to:
Prognosis
ii) Management
6+4