FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
HEMATOLOGY
PAPER III
HEMAT/D/16/48/III
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Clinical and laboratory diagnosis of anti-phospholipid antibody
syndrome (APLA).
How do you manage a case of recurrent pregnancy loss in a case
of APLA?
5+5
2. In deep vein thrombosis/Pulmonary thromboembolism:
How do you manage initially?
How do you do transition from initial treatment?
How do you select anti-coagulants?
How do you monitor and for how long?

3. Enumerate anti-platelet drugs.
Advantages of newer anti-platelet drugs.
Role of platelet transfusion in anti-platelet associated bleeding.

4. Discrepancies between genotypic and phenotypic expressions in:
Hemoglobinopathies
Bleeding disorders.
5+5
5. Classify myeloid neoplasms.
Mention the mutations in polycythemia vera, essential
thrombocythemia and myelofibrosis
What is their potential significance?

6. Name thrombopoietic agents.
What are their side effects?
What is their role in ITP?

7. In acute lymphatic leukemia.
Event free survival in children and adults.
Treatment related mortality.
Long term effects

P.T.O.
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
HEMATOLOGY
PAPER III
8. Enumerate the thalassemic syndromes.
Importance of screening for thalassemia in antenatal mothers.
What are the antenatal diagnostic tests available in different
trimesters of pregnancy?

9. Classify myelodysplastic syndromes.
Clinical features, pathological factors and differential diagnosis of
myelodysplastic syndromes.

10. Newer drugs/products in malignant hematology.
10