FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
IMMUNO-HEMATOLOGY TRANSFUSION MEDICINE
PAPER II
IHTM/D/16/15/II
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:

1. Detail out the important component of computer crossmatch.
Steps to validate the software for computer crossmatch.
6+4
2. Major ABO mismatch allogenic bone marrow transplant.
Preparation of the bone marrow harvest.
Transfusion management.

3. HLA crossmatch.
Methods to enhance sensitivity of identifying HLA antibodies.
5+5
4. Advise patient who insists that she has been typed as A RhD positive.
before in another hospital but has been typed as A RhD negative in your
laboratory.
10
5. Advice a 32 year old regular blood donor who has donated blood five
weeks ago and wants to donate platelets on this occasion.
10
6. A 22 year old medical student has been donating blood once a year
for the past 3 years. No problems were encountered previously but
the third time the donated unit was found to be anti-HIV reactive.
As the in-charge how will you manage the situation?
What actions can be taken to prevent re-occurrence?
5+5
7. TRALI
What is the incidence of TRALI in India and reasons why it is low?
6+4
8. Stem cell enumeration for harvest.
Stem cell harvest and its quality check.
6+4
9. Platelet antigen system.
Post transfusion purpura.
6+4
10. A 35 year old Bengali labourer comes to donate blood in your blood
bank which is in Maharashtra. How will you go about helping him
donate blood?
How will you arrange pre post donation counseling?
5+5