FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
GASTROENTEROLOGY
PAPER II
GASTRO/D/16/10/II
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Role of antiviral treatment for hepatocellular carcinoma
prevention.
Integration of genomic information in the clinical management of
HCC.
Prognosis prediction and staging.

2. IgG4 related sclerosing cholangitis.
IgG4 related autoimmune hepatitis.
Current concepts and diagnosis of IgG4 related pancreatitis.

3. Definition and diagnosis of acute-on-chronic liver failure (ACLF).
Inflammatory response and immune function in ACLF.
Prognosis and biomarkers in ACLF.
Management of ACLF.

4. Diagnosis of drug induced liver injury (DILI).
Drug induced hepatic steatosis.
Anti-tuberculosis therapy induced DILI.

5. Regarding antiviral therapy of Hepatitis
Interferon-free strategies with a nucleoside/nucleotide
analogue.
Interferon-free strategies without a nucleoside/nucleotide
analogue.
Interferon-free regimens in the liver transplant setting.

6. Immunopathogenesis of Hepatitis E virus (HEV).
HEV infection in immunosuppressed patients: Natural history
and therapy.
Hepatitis E vaccine.

P.T.O.
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
GASTROENTEROLOGY
PAPER II
7. Write the following in relation to pancreatic calculi:
Composition.
Endoscopic therapy.
Extracorporeal shock wave lithotripsy.
Pancreatoscopy.
Role of Surgery.

8. Write the following clinical perspectives on sphincter of Oddi
dysfunction.
Definition and consensus criteria.
Pharmacologic therapy.
Endoscopic therapy.
Current state of knowledge.

9. Pancreatic walled off necrosis
Epidemiology.
Diagnosis of WON.
Diagnosis of infection.
Indications for treatment.
Endoscopic management.
2x5
10. Write the following with relation to benign liver tumours:
Imaging of hepatic hemangioma.
Clinical presentation and diagnosis of hepatic adenoma.
5+5