FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PHARMACOLOGY
PAPER-IV
PHARMA/D/17/34/IV
Time: 3 hours
Max. Marks: 100
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space
• Answer all the parts of a single question together.
• Start the question to a question on a fresh page or leave adequate space between
two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Mention ethical issues in biomedical research on
human subjects.
What are the regulatory requirements for conduct of
clinical trial in India?
5+5
2. Application of Biotechnology in Medicine
Orphan drug
5+5
3. Monoclonal antibodies in therapeutics
Role of TNF-alpha blockers in rheumatoid arthritis
5+5
4. Enumerate teratogenic drugs
Role of GnRH in infertility
4+6
5. Current status of malaria and dengue vaccine.
Antibiotic stewardship programme.
5+5
6. Why and where therapeutic drug monitoring is
required?
Mention its usefulness, limitations in patient
management giving example.
5+5
7. Characteristics of various phases of clinical trials
Microdosing
6+4
8. Off label use of drugs with examples.
Medication errors, types and role of pharmacologist
to control in hospital
4+6
9. Recent advances in drug treatment of HIV infection
Signal detection in medicine safety
5+5
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
10. Define protocol violation and protocol deviation.
Give examples.
Composition and responsibilities of Human Ethics
Committee.
5+5