FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
IMMUNO-HEMATOLOGY TRANSFUSION MEDICINE
PAPER-I
IHTM
TIME 3 HOURS
MAX. MARKS 100
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space
• Answer all the parts of a single question together.
• Start the question to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write Short notes on:
1. a. Regulatory T cells (Tregs)
b. Their role in Immune Tolerance
5+5
2. a. Describe pathophysiology of shock.
b. Describe roles of various expanders.
5+5
3. a. Iron metabolism in healthy individual
b. Biochemical markers of iron deficiency
5+5
4. a. Molecular structure of Hepatitis B virus
b. Importance of HBV mutants in transfusion medicine
5+5
5. a. Membrane attack complex in complement activation
b. Antibody mediated hyperacute rejection of solid organ
transplant
5+5
6. a. Schematic illustration of common inheritance patterns
b. General properties of Autosomal Recessive disorders
5+5
7. a. Mechanism of fibrinolysis
b. Natural anticoagulants
5+5
8. a. Types of Hypersenstivity reactions
b. Applied aspects of Type I hypersensitivity reaction in
Transfusion Medicine
5+5
9. a. Laboratory diagnosis of G6PD deficiency
b. Applied aspects in Transfusion Medicine
5+5
10. a. What is reticulated platelet?
b. Describe methods of its detection.
c. Its relevance in Transfusion Medicine