M.Sc. DEGREE EXAMINATION, NOVEMBER 2017
Third Semester
Biotechnology
BIOSTATISTICS
(CBCS 2016 onwards)
Time 3 Hours Maximum 75 Marks
Graph sheets are required for few questions.
Part A (10 x 2 20)
Answer all questions.
1. Grouped variance Write a short note.
2. What is mean by Inter quartile range?
3. Line graphs Explain shortly.
4. Write a short note on frequency polygon.
5. What do you mean by survival function?
6. Discuss the Gaussian distribution.
7. What do you understand from null hypothesis and
alternate hypothesis?
8. Gene pool Discuss.
9. Write a short note on level of significance.
10. Simple linear regression Discuss.
Sub. Code
501707
RW-842
2
Ws15
Part B x 5 25)
Answer all questions by choosing either or
11. For the following data on two samples calculate
range and standard deviation.
Sample 1 1.2 1.4 1.6 1.8 2.0 2.2 2.4
Sample 2 1.2 1.6 1.7 1.8 1.9 2.0 2.4
Or
Write a short note on grouped mean and coefficient
of variation.
12. Write a short note on types of numerical data with
suitable examples.
Or
For the data on craniofacial morphology of patients
diagnosed with obstructive sleep apnea syndrome in
healthy male subjects, construct frequency
distribution and frequency polygon.
33.57 27.78 40.81 38.34 29.01 47.78 26.86 54.33 28.99
25.21 30.49 27.38 36.42 41.50 29.39 24.59 41.75 44.68
24.49 33.23 47.09 29.07 28.21 42.10 26.54 27.74 33.48
31.44 30.08
13. Define confidence interval and describe the
procedure of constructing confidence interval of two
means.
Or
Explain the role of standard deviation in
constructing confidence interval of a mean.
RW-842
3
Ws15
14. What is a p-value? Describe the role of p-value in
testing of hypothesis.
Or
Define the following terms
Allele frequency
Prevalence and
Specificity.
15. The data is on wing length of 13 sparrows of
various ages fit a simple linear regression for
this data
X 3 4 5 6 8 9 10
Y 1.4 1.5 2.2 2.4 3.1 3.2 3.2
X 11 12 14 15 16 17
Y 3.9 4.1 4.7 4.5 5.2 5.0
Or
Write a short note on simple correlation coefficient
and test for correlation.
Part C x 10 30)
Answer any three questions.
16. Explain the following terms with suitable examples
Mode
Coefficient of variation and
Grouped mean.
17. For the given data construct the Box-plot and give its
interpretation.
35 32 31 43 39 60 36 12 54 45 37 53 45
23 64 10 34 22 36 45 55 44
RW-842
4
Ws15
18. Describe in detail the procedure of comparing two
survival curves using confidence interval.
19. Define ROC curve and explain its role in decision making
with a suitable example.
20. Define probability and give an account of Bayes theorem
with an application to genetics.