M.Sc. DEGREE EXAMINATION, NOVEMBER 2017
Third Semester
Biotechnology
Core XII — BIOINFORMATICS
(CBCS 2016 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 x 2 20)
Answer all questions.
All questions carry equal marks.
1. Bioinformatics.
2. GenBank.
3. Local alignment.
4. ClustalW.
5. Contig assembly.
6. DNA.
7. MASCOT.
8. Tandem.
9. Pharmacogenomics.
10. Drug designing.
Sub. Code
501301
RW-837
2
Ws5
Part B x 5 25)
Answer all questions choosing either or
11. Briefly explain EMBOSS.
Or
Describe about an open source software.
12. Give a detailed account on pair wise alignment.
Or
Describe about the Phylogenetic analysis.
13. Describe a RNA structure analysis tool.
Or
Explain about q PCR data analysis.
14. Write a short notes on Swiss PDB Viewer.
Or
Describe about Rasmol.
15. Write short notes on virtual screening.
Or
Give a detailed account on ADMET.
Part C x 10 30)
Answer any three questions.
16. Describe in detail about biological databases.
17. Give a detailed account on sequence alignment tool.
RW-837
3
Ws5
18. Explain the protein tertiary structure predication
methods with an example.
19. Narrate the protein-protein interaction tools.
20. Write a note on
Ligand based drug designing
Structure based drug designing.
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