Exam Details
| Subject | sterile dosage forms | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | March, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm. (Semester VII) (CGPA) Examination, 2018
Sterile dosage forms
Day and Date Thursday, 3-5-2018 Max. Marks 70
Time 3.00 p.m. to 6.00 p.m.
I. MCQ's (1×15=15)
Which is permitted limit for solid content in WFI
0.1 ppm 10 ppm 0.2 ppm 100 ppm
Isotonicity of an injections can be calculated by
Freezing point method
Molar concentration method
Molecular weight
Both and
To make isotonic opthalmic solution how much of basic acid is needed
5 0.9 4 1.9
is/are the toxicity modifier in sterile preparations.
NaCl Boric acid
Dextrose All of the above
Which of the following is concerned with particle aggregation in parenteral suspension
Injectability Syringe ability Zeta potential All of these
The cold DOP test is useful for the evaluation of
HEPA Temperature sensitivity
Blowers All of these
Reduction of microbial population by 90% is known as
z-value f-value D-value N-value
As per GMP, for dilution of disinfectant which kind of water should be used
SWFI WFI Distilled water All of these
pH of human tear is
1 to 3 3 to 4.5 5.5 to 6.1 7.1 to 7.6
P.T.O.
SetP
Seat
No.
Set P
SLR-TA 44 *SLRTA44*
10) Viscocity enhancer in opthalmic preparation is
PVA Povidone Dextran Macrogel
11) Suspensions should never be administer by route.
Iv Im Subcutaneous Endodermal
12) Which one of used for the formulation of LVP and need not to be sterile at the time of formulation
WFI SWFI
Bacteriostatic WFI All of these
13) Which of the following may not be additive in LVP
Preservative Buffers Co-solvent None of these
14) Which of the following routes provides maximum bioavailability
Iv Im Oral Subcutaneous
15) A clarity test in parenteral formulation is intended to control which of the following
Opacity Colour Solubility Particulate matter
II. Solve any five
Give an idea about large volume parenterals.
Write a note on parenteral packaging.
Discuss sterility testing.
Write a note on SUPAC guidelines.
Discuss merits and demerits of parenteral formulations.
Discuss ocular bioavailability.
III. Answer any three (10×3=30)
Discuss majors to be utilized for the environmental control in parenteral manufacturing.
Give in detail account of parenteral processing.
Discuss different methods of sterilization and environmental validation.
Discuss FFS technology in parenteral formulations.
Sterile dosage forms
Day and Date Thursday, 3-5-2018 Max. Marks 70
Time 3.00 p.m. to 6.00 p.m.
I. MCQ's (1×15=15)
Which is permitted limit for solid content in WFI
0.1 ppm 10 ppm 0.2 ppm 100 ppm
Isotonicity of an injections can be calculated by
Freezing point method
Molar concentration method
Molecular weight
Both and
To make isotonic opthalmic solution how much of basic acid is needed
5 0.9 4 1.9
is/are the toxicity modifier in sterile preparations.
NaCl Boric acid
Dextrose All of the above
Which of the following is concerned with particle aggregation in parenteral suspension
Injectability Syringe ability Zeta potential All of these
The cold DOP test is useful for the evaluation of
HEPA Temperature sensitivity
Blowers All of these
Reduction of microbial population by 90% is known as
z-value f-value D-value N-value
As per GMP, for dilution of disinfectant which kind of water should be used
SWFI WFI Distilled water All of these
pH of human tear is
1 to 3 3 to 4.5 5.5 to 6.1 7.1 to 7.6
P.T.O.
SetP
Seat
No.
Set P
SLR-TA 44 *SLRTA44*
10) Viscocity enhancer in opthalmic preparation is
PVA Povidone Dextran Macrogel
11) Suspensions should never be administer by route.
Iv Im Subcutaneous Endodermal
12) Which one of used for the formulation of LVP and need not to be sterile at the time of formulation
WFI SWFI
Bacteriostatic WFI All of these
13) Which of the following may not be additive in LVP
Preservative Buffers Co-solvent None of these
14) Which of the following routes provides maximum bioavailability
Iv Im Oral Subcutaneous
15) A clarity test in parenteral formulation is intended to control which of the following
Opacity Colour Solubility Particulate matter
II. Solve any five
Give an idea about large volume parenterals.
Write a note on parenteral packaging.
Discuss sterility testing.
Write a note on SUPAC guidelines.
Discuss merits and demerits of parenteral formulations.
Discuss ocular bioavailability.
III. Answer any three (10×3=30)
Discuss majors to be utilized for the environmental control in parenteral manufacturing.
Give in detail account of parenteral processing.
Discuss different methods of sterilization and environmental validation.
Discuss FFS technology in parenteral formulations.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms