B. Pharm. (Semester IV) (New CBCS) Examination, 2018
organic Chemistry III
Day and Date Thursday, 13-12-2018 Max. Marks 70
Time 2.30 p.m. to 5.30 p.m.
I. Choose the most appropriate one from the following answers (1×15=15)
Order of migration of groups in Wagner-Meerwein rearrangement is
Methyl t-Butyl Phenyl Phenyl Methyl t-Butyl
t-Butyl Phenyl Methyl Phenyl t-Butyl Methyl
Addition of water to this alkene is faster in
Ethene Propene E-Butene Z-Butene
Fries rearrangement leads to products with substitution at
positions.
Ortho Para
Meta Both ortho and para
Markovnikov's addition is seen with addition reaction.
Hydration Halogenation
Hydroboration-Oxidation Hydrogeneration
The term anti-periplanar means
±30° same side ±60° same side
±30° opposite side ±150° opposite side
Willgerodt rearrangement reaction belongs to type.
Electrophilic Aromatic Radical Nucleophilic
The group with highest priority in according to CIP rules
-CCl3 O ≡ N None
Halogenation reaction is
Stereoselective Regioselective
Stereospecific Chemoselective
Seat
No. Set P
Set P
SLR-TV 26 *SLRTV26*
isomers are generated by rotation of groups around a C C
bond.
Geometric Conformational
Enantiomers None
10) Identify the geometrical isomer from the following
None
11) Pyrolysis requires
Solvent Heat Light Agitation
12) Chose correct reagent for completing the following reaction
R1CROHCH2R2 R1 CR CH R2
HCl, H2O NaOH NaOET H2O
13) In a substitution reaction, small sized, strong nucleophiles lead to
type of reaction.
SN1 SNi SN2 E1
14) Identify the reaction type
Pyrolysis Electrocyclic Cycloaddition Sigmatropic
15) differentiates mesomers from enantiomers.
Symmetry Rotation around bond
Connectivity Rigidity
II. Answer any five questions of the following
Define addition reaction. Explain a method in which synaddition occurs.
Describe Curtius rearrangement reaction.
Enlist the role of conformation in chemistry and biology. Describe briefly
Butane's conformational analysis.
How are geometrical isomers named Explain.
Write a note on pericyclic reactions including their synthetic applications.
Define and give an example for Tautomer; Mesomer; E-Z-isomer;
Rotamer.
III. Answer any three questions of the following (3×10)
Describe SN1 and E2 reaction taking an example. Add note on
stereochemistry.
Explain Claisen rearrangement and Dakin oxidation.
Describe chemical and physicochemical methods of separation of
enantiomers.
Write a note on
Diels Alder reaction
Cope elimination.