B.Pharm. (Semester II) Examination, 2018
Pathophysiology (new CBCS)
Day and Date Friday, 14-12-2018 Max. Marks 75
Time 2.30 p.m. to 5.30 p.m.
1. Multiple Choice Questions (20×1=20)
Decrease in size and number of parenchymal cell is called as
Dystrophy Atrophy Atopy Metaplasia
Which of the following is a cell mediated mediator of inflammation
Adrenaline Pyridoxamine
Histamine All of the above
Monitoring the progress of disease condition is termed as
Diagnosis Prognosis
Dialysis Therapeutic drug monitoring
Symptoms of diabetes mellitus do not include
Pruritis Polyphagia
Vulvitis Polydipsia
The condition in which urine production is decreased below 500 ml per day
is called as
Polyria Oligouria
Anuria Ketouria
Quantitative abnormalities of Polypeptide globin chain synthesis leads to
Thallassaemia Hemophilia
Hematuria Polycythemia
The major location of occurrence of Emphysema is
Bronchus Trachea
Bronchioles Acinus
Which of the following Hepatitis is having the longest incubation period
Hepatitis A Hepatitis B Hepatitis C Hepatitis D
Which of the following type of cell in GIT is majorly responsible for secretion
of mucus
Chief cell Parietal cell
Goblet cell Peptic cells
10) The duration of the initial asymptomatic incubation period in typhoid fever
is about
2 days 2 weeks 2 months 2 years
11) The study of causes of diseases is known as
Epidemiology Etiology
Histology Morphology
12) Spread of tumour to distant tissues by invasion is termed as
Dysplasia Metaplasia
Oncogenesis Metastasis
13) The causative organism for syphilis is
Salmonella typhi Vibrio cholera
Tropodema pallidum Clostridium tetani
14) Loss of appetite is known as
Insomnia Nausea Anorexia Alopecia
15) A sudden rise in blood pressure above 200/140 mmHg is termed as
Pre-hypertension Malignant hypertension
Benign Hypertension Isolated systolic hypertension
16) Progressive dementia is the feature of
Parkinson's disease Epilepsy
Alzheimer's disease Psychosis
17) Which of the following is not an example of negative feedback mechanism
Thirst
Renin- Angiotensin- Aldosterone Pathway
Platelet aggregation
Release of thyroid hormone
Set P
*SLRTV8* SLR-TV 8
18) change in reversible injury is also known as glassy change.
Hyaline Fibrinoid Hydropic Fatty
19) Pathogenesis of bronchial asthma involves development of
Deficiency of α-1 antitrypsin Airway damage
IgE- sensitized mast cells Ciliary paralysis
20) The parameter which can describe the blood sugar level over a period of
3 months is
Fasting sugar Post-prandial sugar
Random sugar Glycosylated hemoglobin
2. Long answers. (Answer two out of three) (2×10=20)
Describe the etiopathogenesis of Peptic Ulcers. Differentiate between gastric
and duodenal ulcers.
Write a note on pathogenesis and clinical manifestations of Parkinson's and
Alzheimer's disease.
Classify hypertension. Describe the etiology and clinical complications of
hypertension.
3. Short answers. (Answer seven out of nine)
Define Homeostasis. With the help of one example, describe the role of
negative feedback mechanism.
Describe the process of emigration of leucocytes in inflammatory condition.
What are the causes and symptoms of Chronic Bronchitis
Write a note on causes of Acute Renal Failure.
Describe the etiology and role of genetics in development hemophilia.
Distinguish between clinical features of hyperthyroidism and hypothyroidism.
Explain the process of carcinogenesis.
Describe the causes and clinical manifestations of Rheumatoid arthritis.
Write a note on the causative organism, mode of transmission and clinical
complications of AIDS.