Exam Details

Subject molecular biology
Paper
Exam / Course m.sc
Department
Organization central university
Position
Exam Date 2011
City, State telangana, hyderabad


Question Paper

ENTRANCE EXAMINATION-2011 M.Sc Molecular Microbiology
Time: 2 hours Maximum Marks: 100
HALL TICKET NO.

lNS1;RUCTIONS

Please read carefuUy before answering the questions:
I. Enter your Hall ticket number both on the top of this page and on the OMR answer sheet without fail.
2.
Answers are to be markcd only on the OMR answer shed following the instructions provided there upon.

3.
Hand over both the question paper booklet and OMR answer sheet at the end


of examination.
4. The question paper contains 100 questions Question Nos. 1-25 and Part-B: Question Nos. 26-100) of multiple choice typed in 20 pages, including this page. One 2MB sheet is provided separately. Please check.
S. The marks obtained in Part-A will be used for resolving the tie cases.
6.
Each question carries one mark.

7.
There is negative marking for wrong answers in PARTS A and B. For each wrong answer, 0.33 of a mark will be deducted.

8.
Calculators and mobile phones are not allowed.




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PART-A

I. A reddish blue-green algae that occasionally grows in great abundance, impacts a red color to water -the red sea is so named for this
A. Trichodesmium erytMaeum
B. Synechocystis sp. PCC6803
C. Nostoc punctiforme
D. ProchlorococCU!J sp.
2. The mRNA codons ofamino acids coding for a part of a polypeptide chain are 5'­UGU-GAU-eAC·UAG-GAU-AAG-eAC·3'. Which DNA base sequence would provide the code for this section ofpolypeptide?
A. 5'-ACA-CTA-GTG-ATC-CIT-ITC-GTG-3'
B. 5'-ACA-eTA-GTG-ATC-CIT-ITC·GTC-3'
C. 5'·TCT-eIT-GTG-ITC-eIT-ITC-GTG·3'
D. 5'·ACA-CTA·GTG·ATC-eTA·ITC·GTG·3'
3. The IUPAC name ofthe compound with chcmical formula given as
HO-CH2-eH2-CH2-0H is
A. 1,2,3-Propanediol
B. 1,2,3,-Ethanediol
C. 1,3-Propanediol
D. 1,2,3-propanetriol
4. Which among the following is not a characteristic ofphotosynthesis in plants?
A. The oxygen evolved is derived from photolysis ofwater
B. Light energy is fllSt captured by PS-I and electrons are then passed to PS-II
C. ATP is synthesized by an electron transport chain connecting PS-I and PS·II
D. Light-dependent reactions generate ATP and NADPH and light. independent reactions use energy-rich molecules to reduce C02
5. Formation of 'ossicles' to produce a tough endoskeleton is a general structural feature of
A. Molluscs
B. Arthropods
C. Echinoderms
D. Water bugs
6. The union of a hypha with another hypha resulting in intercommunication of their genetic material is called as
A. Anastomosis
B. Anamorphosis
C. Anthracnosis
D. Acervulensis
7. In'human ABO blood group system, there are six possible genotypes but only four phenotypes. An explanation ofthis is ABO blood groups are controlled by
A. One gene locus with three co-dominant alleles
B. One gene locus with two co-dominant alleles and one recessive allele
C. One gene locus with two dominant alleles and one recessive allele
D. One gene locus with three dominant alleles
8. To prepare a solution of 50 mM Tris (pH 8.0) and ImM EDTA, the stock solutions of2 M Tris (pH 8.0) and 500 mM EDTA should be mixed as shown in
A. 25 ml of2 M Tris and 0.2 ml of500 mM EDTA in 1000 ml
B. 2.5 ml of2 M Tris and 0.2 ml of 500 mM EDTA in 100 ml
C. 2.5 ml of2MTris and2ml of500mMEDTA in 1000ml
D. 5 ml of2 M Tris and 0.2 ml of 500 mM EDTA in 100 ml
9. Which of the following is true ofa species that has a chromosome number of2n 16?
A. The species has 16 different types ofchromosomes
B. A gamete from this species has 8 chromosomes
C. The species has 16 homologous pairs
D. All ofthe above
10. Match the following vitamins listed as M N 0 with the symptoms associatcd with their deficiencies given as C D.
L. Vitamin-E I. Liver degeneration
M. Vitamin ·C 2. Xerophthalmia
N. Pantothenic acid 3. Scurvy disease
O. Vitamin-A 4. Fatty acid oxidation deficiency
A. M·3, 0-2
B. L·2, N·I, 0-3
C. N·2, 0-4
D. 0-2
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II. Microcosms refer to
A. DNA fragments of microorganisms
B. A laboratory system that attempts to stimulate a natura1 habitat
C. A system where microorganisms are grown in space
D. Small changes that occur in microorganisms due to toxic chemicals
12. In order to convert a mRNA to a copy of cDNA in molecular biology experiments this enzyme is frequently used
A. RNA dependent RNA polymerase
B. DNA dependent DNA polymerase
C. T4 DNA Kinase
D. Reverse Transcriptase
13. Which ofthe following compound has a chiral structure?
A. CH3CHOH
B. CH2=CH-CHCH3-NH3
C. CH3CH2 CHCH2CH3-Br
D. (C2H5)2 CH-Br
14. At night, transpiration usually does not occur because most plants have their stomata closed. When soil moisture level is high, water will enter plant roots, becausc the water potential of the roots is lower than that ofthe soil solution. The root pressure forces some water to exude through special leaf tips. This process is called as and is occurring through special structures called as .
A. Hydrolysis and xylem vessels
B. Transpiration and stroma
C. Guttation and hydathodes
D. Gummosis and xylem vessels
15. A transitional fossil which formed a link between a dinosaur and a bird is
A. Deinonydrosaurs
B. Archaeopteryx
C. Pteranodon
D. Brachylophosaurus

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16. Identical antibodies produced by a siDgle clone of lymphocytes which IlJe reacting only with one of the antigenic determinants ofa pathogen or protein
A. Immunoglobulins
B. Polyclonal antibodies
C. Monoclonal antibodies
D. Mimotopes
17. 'Katte disease' of cardamom, 'kadang kadang' disease of coconut, 'laughing death' disease of animals and 'Witch's broom' disease of higher plants arc caused respectively by
A. Viroid, Prion and Phytoplasma
B. Virus, Viroid, Prion, and Phytoplasma
C. Phytoplasma, Viroid, Virus, and Bacteria
D. Prion, Virus, Phytoplasma and Viroid
18. Differentiation of a vegetative shoot meristem into a floral meristem in a temperate plant is mediated by an extemal stimulus and the process is called vernalization. Which among the following stimuli leads to the process of vernalization?
A. Abscission ofapical meristems to induce flowering
B. Bahar treatment by excision of roots
C. Chilling ofapical meristems preceding anthesis
D. Heat shock treatment of apical meristcms preceding anthesis
19. A radially symmetrical relaxation and contraction movement of muscles which propagates in a wave like motion in smooth muscles ofdigestive tract is called
A. Peristalsis
B. Gastrostalsis
C. Epistalsis
D. Hyperstalsis
20. The free energy change of a reaction at equilibrium is
A. Is always positive
B. Is always zero
C. Is always negative
D. Positive, negative or zero
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21. When a mustard plant showing sporophytic type of self incompatibility mating system produces multiple alleles SI, S2 and S3 with an order of domillllDCe given as S which type of mating among the following combinations would be highly incompatible?
A. Pollen grain has S1allele and ovary has SIS2 alleles
B. Pollen grain has SI allele and ovary has S2S3 alleles
C. Pollen grain has S2 allele and ovary has S1S3 alleles
D. Pollen grain has S3 allele and ovary has S1S2 alleles
22. The famous Irish famine of 1840's was caused by the fungal pathogen
A. Pernospora porositica
B. Plasmopara vilicola
C. Phylophlhora injeslans
D. Cladosporium ftlvum
23. ABC model has been demonstrated to regulate different whorl formation during floral development in Arabidopsis IhaliaM, a model plant. The three homcotic genes B and C are required for the development of a normal flower. IdentitY the gene or gene combination that should .express for normal development of stamens.
A. AandB
B. Band C
C. C alone
D. AandC
24. When salicylic acid is heated with acetyl chloride or acetic anhydride in the presence ofphosphoric acid, the product formed is acetyl salicylic acid; which is used in medicine as
A. Analgesic compound
B. Anaesthetic compound
C. Insecticide
D. Sedative and hypnotic medicine
2S. Carbon dioxide, methane and chloro-f1ouro compounds are considered as green house gases because they can absorb
A. Ultraviolet radiation
B. X-ray radiation
C. Visible light radiation
D. Long wave infrared radiation
6



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26. Largest and most complex sea weeds belong to one oftbe following groups
A. Red algae
B. Brown algae
C. Green algae
D. Dinoflagellates
27. Dark phenolic compounds extracted from bark and leaves of oak plants are used to render leather in leather industry. They are
A. Resins
B. Terpenes
C. Alkaloids
D. Tannins
28. Which among the following is a micronutrient required for plant growth?
A. Chlorine
B. Sodium
C. Potassium
D. Zinc
29. The five-carbon sugar ofCalvin-Benson cycle that originally captures Co, is
A. Pyruvate
B. Phosphoglyceric acid
C. Phosphoglyceraldehyde
D. Ribulose bisphosphate
30. Chromosome compliment with 2n number ofchromosomes is called
A. Trisomy
B. Nullisomy
C. Monosomy
D. Tetrasomy
31. Which among the following genera is not a primary producer?
A. Chlorella
B. Rhodospirillum
C. Rhodococcus
D. Spirulina
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32. Whatistheploidylevel ofanendospennofmaize?
A. 2n
B. 3n
C. n
D. 4n
33. Name the economically important part ofcotton plant
A. Stem
B. Flower
C. Boll
D. Fuzz
34. A stem parasite among the following is
A. Striga
B. CUSCut8
C. Orabanche
D. Silvcr oak
35. During which stage of cell division the genctic material gets duplicated along with its associated nuclear proteins?
A. G I phase of Interphase
B. G2 phase ofInterphase
C. S phase of Interphase
D. Metaphase I
36. 'Microphylls' in Lycopodium, a club moss are miniature structures of
A. Leaves
B. Male sporangia
C. Female sporangia
D. Corm like stem
37. Pteridophytes are vascular cryptograms which contain in their life cycle
A. A haploid prothalium and a diploid sporophyte
B. A diploid prothalium and a haploid sporophyte
C. A haploid prothalium and a haploid sporophyte
D. A diploid prothalium and a diploid sporophyte

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38. Epiphylls are
A. Openings in the bark ofstem
B. Moss growing on leaves
C. Rock-borne cryptograms
D. Vents in the leaves
39. A plant's overgrowth due to increased cell division and abnormal cell enlargement are respectively called as
A. Hyperplasia and hypertrophy
B. Hypertrophy and hyperplasia
C. Hypertrophy and hypervirulence
D. Hyperplasia and hypervirulence
40. Phytochrome in plants is sensitive to
A. Red light
B. Green light
C. Yellow light
D. Red and far red light
41. Algae and other submerged aquatic plants float in water during day time but sink at night
A. loose weight at night because fishes eat them
B. They become buoyant in light due to oxygen bubbles accumulated by photosynthesis but at night this oxygen is used up in respiration.
C. They becomes light due to consumption offood by photorespiration
D. They come up to enjoy sunshine
42. Which among the following is a thigmotrophic response in plant
A. Growth of roots towards water
B. Curling of a tendril to the support
C. Orientation ofshoot to sun
D. Peg formation in peanut
43. The male inflorescence ofa maize plant is called as
A. Cob
B. Ear
C. Tassel
D. Androdioecium




44. Match the type of cell listed as N and 0 to the tissue or part of the cell given as C and D.
L. Tl1ICheid 1. Phloem
M. Seive element 2. Meristematic tissue
N. Parenchyma 3. Cell wall offruit
O. Stone cell 4. Xylem
A. 0-3
0-3

C. 0-I
D. L-I. 0-2
45. A cephalopod mollusc among the following is
A. CuttJc fish
B. Ray fish
C. Starfish
D. Sea horse
46. Polychaetcs and oligochaetes belong to one ofthe following groups
A. Annelids
B. Orthropods
C. Molluscs
D. Millipeds
47. Presence of an exoskeleton, a segmented body and jointed -appendages are characteristic features of
A. Annelids
B. Chordates
C. Echinoderm
D. Arthropods
48. The book 'Origin of Species" was written by
A. Alfred Russel Wallace
B. Lamarck
C. Gregor Johann Mendel
D. Charles Robert Darwin
49. The enzyme present in saliva is
A. Pepsin
B. Trypsin
C. Ptyalin
D. Myonin
50. The well known phrase "Ontogeny recapitulates phylogeny" describing stages
of animal development going through adult stages of distant ancestors was given by
A. Robert Koch
B. Theodar Schwann
C. Sutton and Boveri
D. Ernest Haekel
51. Match the following
L. Anthrax I. Hannone
M. Rabies 2. Bacillus sp.
N. Hepatitis 3. Zoonotic disease
O. Humulin 4. Recombinant vaccine
A.
B.
c.


D.



52. Trypanosomiasis is a disease transmitted by
A. Mosquito
B. Fire-fly
C. May-fly
D. Tsy-tsy
53. A light receptor in certain bacteria resembles to that found in the eyes ofanimals. What is the bacterial light receptor called?
A. Photochrome
B. Opsin
C. Baeteriorhodopsin
D. Rhodopsin


54. A protein whose absence causes a cell to get transformed into carx:erous cell is refetTed as
A. Tumor suppressor protein
B. Oncoprotein
C. Apoptotic protein
D. Tumor necrosis factor
55. Commensalism is
A. A type of symbiosis in which one individual gains from the association and thc other is neither harmed nor benefited
B. A type of symbiosis in which one individual gains from the association by harming the other
C. A type of symbiosis in which neither ofthe individuals gains from each other nor is harmed
D. A type ofsymbiosis in which both the individuals gain from each other but fmally harm one other
56. Birds replace their feathers periodically in a process called
A. Shedding
B. Migration
C. Preening
D. Molting
57. Vaccination is an example of
A. Naturally acquired active immunity
B. Artificially acquired active immunity
C. Naturally acquired passive immunity
D. Synthetic acquired passive immunity
58. Most naked animal viruses penetrate a host cell by
A. Encapsidation
B. Exocytosis
C. Endocytosis
D. Endosome fusion
59. Epinephrine is secreted from
A. Hypothalmus
B. Postcrior Pituitary
C. Adrenal medulla
D. Anterior pituitary 12
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60. The science dealing with study offishes is called
A. Ornithology
B. Icthyology
C. Bryology
D. Fisheries
61. A mollusc is a source for one ofthe following luxury goods
A. Pearl
B. Sea silk
C. Imperial dye
D. All the above
62. Stiffbristles present on the body of an earthworm to attach to a support inorder to prevent back sliding are called
A. Septae
B. Setae
C. Cilia
D. Cirri
63. An organism being borne as a male but later changes into a female is referred as
A. Androdioecious
B. ProtanOOc
C. GynanOOc
D. Gynomonoecious
64. The most abundant organic compound in the biosphere
A. Pectins
B. Cellulose
C. Starch
D. Glycogen
65. An unbranched form ofglucose polymer present in starch molecule is called
A. Amylopectin
B. Amylose
e.
Amylase

D.
Maltose


13


66. Sterol campestrol derived plant growth regulator which could stimulate cell division and elongation in plants even at low levels arc
A. Polyamincs
B. Cyotkinins
C. Gibbcrcllins
D. Brassinostcroids
67. Match the following harmones listed as N and 0 to their roles in plant growth and development given as C and D.
L. Cytokinin 1. Cell elongation
M. Ethylene 2. Dormancy
N. Auxins 3. Cell division
O. Abscissic acid 4. Fruit ripening
A. 0-2
B. Q-4
C. 0-2
D. M·2, 0-3
68. The process by which Adenosine triphosphatcs (ATPs) arc synthesized from Adenosine diphosphates (ADPs) using proton motive force that get pumped through the intermembranc spaces ofmitochondria is by the process called
A. Reductive phosphorylation
B. Oxidative carboxylation
C. Oxidative phosphorylation
D. Reductive carboxylation
69. What kind of reaction performs both synthesis and decomposition?
A. Endergonic reaction
B. Fusion reaction
C. Fission reaction
D. Exchange reaction
70. Glyphosate is a
A. Fertilizer
B. Antibiotic
C. Herbicide
D. Hormone
14


v

71. For separation of protein molecule Polyacrylamide gels are commonly used. During preparation of gels APS and TEMED are used. What are APS and TEMED?
A. Ammonium persulphate and tricbloroethelenemonoethyldiamine
B. Ammonium persulphate and tetramethylethylenediamine
C. Amino acid with pure sulphur and tetramethylethylenediamine
D. Ammonium persulphate and TEMED is not an abbreviated term, rather it itself is a name ofa compound.
72. IdentifY the one among the following which is not used as food preservative
A. Ethyl acetate
B. Sodium diacetate
C. Benzoic acid
D. Sodium nitrite
73. In which of the following processes metabolic substrates and end products are organic molecules
A. Respiration
B. Photosynthesis
C. Fermentation
D. Photolysis ofwater
74. What is a Coenzyme?
A. Synonym for an enzyme
B. Antonym for an enzyme
C. Protein in nature and is a substrate for an enzyme
D. Nonprotein organic molecule and is a helper ofan enzyme
75. Cephalosporins inhibit
A. Nucleic acid synthesis
B. Protein synthesis
C. Peptidoglycan synthesis
D. Cytopasmic membrane potential
76. Beta particles have
A. ve charge and negligible mass
B. +ve charge and some mass
C. -ve charge and negligible mass
D. -ve charge and some mass
15
77. Which ofthe following pairs is mismatched?
A. Mataehromatic granules -stored phosphates
B. Sulfur granules -energy reserve
C. Lipid inclusions -poly fl-hydroxybutyrlc acid
D. Polysaccharide granules -stored starch
78. The precursor for fatty acid biosynthesis is
A. Histidine
B. Phenylalanine
C. Malonyl CoA
D. Acetyl CoA
79. Which among the following is nota C4 compound
A. Malate
B. Oxaloacetate
C. lsocitrate
D. Fumarate
80. Nickel is a component ofthe enzyme:
A. Urease
B. Amylase
C. Nitrogenase
D. Nitrate reductase
81. One ofthe following is an essential amino acid for humans
A. Glutamic acid
B. Proline
C. Threonine
D. Serine
82. White rust of crucifer is the disease caused by the genus
A. Alternaria
B. Phytophthora
C. Albugo
D. Claviceps
83. An organism panly or totally deficient of a substance. the addition of which significantly promotes the growth ofthe organism is termed as
A. Biotroph
B. Auxotroph
C. Heterotroph
D. Anamorph
84. The swollen tip of a fungal hypae which helps in the attachment and penetration ofthe germ tube is called
A. Ascocarp
B. Haustorium
C. Appressorium
D. Acervulus
85. Inability of a pathogen to infect a plant because the plant is not a host of the pathogen either due to lack of something in the plant that the pathogen needs or the presence of substances which are incompatible with the paihogen is called as
A. Acquired resistance
B. Non-host resistance
C. Plant Pathogenesis
D. Systemic acquired resistance
86. Gas vacuoles are present in
A. Anabaena flos-aquae
B. Bacillus subtilis
C. Acanthurus nigrofuscu.,
D. Mycobacterium tuberculosis
87. Geosmins are
A. A group ofantibiotics produced by Streptomycetes
B. Streptomycete metabolites that give characteristic earthy odor ofsoil
C. Polyenes produced by Streptomyces
D. A group ofStreptomyces which are useful for mining
88. World environment day is celebrated on
A. 8thMay
B. 5th June
C. 13th August
D. 9th September
89. A subunit of virus's protein coat is called as
A. Capsid
B. Nucleocapsid
C. Icosahedran
D. Capsomere
90. PencilJin acts as an antibiotic in susceptible bacteria by iIlterfering with
A. Cell wall formation
B. Protein synthesis
C. Electron transport chain
D. DNA synthesis
91. Molecular chaperones are class of proteins that facilitate
A. Proper folding of newly synthesized proteins
B. Unfolding of newly synthesized proteins
C. Degradation of newly synthesized proteins
D. Targeting of newly synthesized proteins
92. Which of the following honnone is produced by Agrobacterium during tumor gall formation
A. Abscissic acid
B. Ethylene
C. Gibberellic acid
D. Cytokinins
93. Genetic material in eukaryotes and some prokaryotes are mostly made up of DNA. However, we can see diverse genetic materials like single stranded linear and circular DNA double stranded RNA (ds positive sense RNA RNA) negative sense RNA sense) and ambisense RNA as genetic material in one of these organisms
A. Viroids
B. Micoplasmas
C. Viruses
D. Prions
94. Microorganisms growing on very high nutrient are referred as
A. Oligotrophus
B. Lithotropbs
C. Copiotrophus
D. Autotropbs
95. A person heterozygous for the recessive gene for cystic fibrosis marries a person who does not carry or possess the trait homozygous dominant). What is the probability that the couple's first child will have cystic fibrosis?
A. 0.0
B. 0.25
C. 0.5
D. 1.0
96. 1be evidence that DNA is the genetic material came from the experiments of
A. Morgan
B. Griffith
C. Watson and Crick
D. Avery, Macleod and McCarty
97. How many gametes an: produced by a diploid individual which is heterozygous for 5 genes?
A. 8
B. 16
C. 32
D. 64
98. When two genes are situated very close together in a chromosome
A. Percentage ofcrossing over between them is very high
B. Hardly any linkage is detected
C. No crossing over can ever take place between them
D. Only double crossove can take place between them
99. When a pea plant with yellow endosperm as a dominant trait was mated with another pea plant with a recessive green endosperm, the resultant FI showed both yellow and green cndosperm.in the ratio of I respectively. What would be the genotype ofthe parents used in the cross?
A. One of the parents is heterozygous dominant with yellow endosperm and the other parent is a recessive homozygote with green endosperm
B. One ofthe parents is homozygous dominant with yellow endosperm and the other parent is homozygous recessive with green endosperm
C. Both the parents have homozygous yellow endosperm
D. Both the parents have bomozygous green endosperm


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100. There can be charactcn in children which are different from either of their parents. This is due to the phenomenon called
A. Replication
B. Variation
C. Heredity
D. Inheritance


Subjects

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