M.Sc. DEGREE EXAMINATION, NOVEMBER/DECEMBER 2017.
Third Semester
Chemistry
Paper IV BIO-ORGANIC CHEMISTRY
(Common for all Specialization in Chemistry)
2 20134
Time 3 Hours Max. Marks 75
SECTION — A
Answer any FIVE questions. 5 25 Marks)
(Short answer question)
1. Explain enzyme mechanism for Lysozyme.
2. Explain Asymmetric cyanohydrin formation.
3. Write applications of recombinant DNA technology in diagnosis of diseases.
4. Explain the principles of Finger printing technology.
5. Write about vitamin derived coenzymes.
6. Explain the biological functions of pyridoxal phosphates.
7. Write the general properties of amino acids.
8. Explain the classification of proteins with suitable examples.
SECTION — B
Answer ALL questions choosing ONE from each Unit.
(Essay type questions) 12½ 50 Marks)
9. Explain the transition state Theory of Acid base catalysis with examples.
Or
10. Discuss the Enzyme mechanism for the following
Synthesis of amino acids.
Transformation of lipases.

11. Explain the basic mechanism of Recombinant DNA technology. Write its
applications in the production of pharmaceuticals.
Or
12. Discuss the mechanism of Fermentation Technology. Write its applications in the
production of drugs and drug intermediates.
13. Explain the structure and biological functions of Thiamine Pyrophosphate
and Nicotinamide Adenosine Dinucleotide (NAD).
Or
14. What are coenzymes? Discuss the structure and biological function of
S-adenosyl methionine Flavin mono nucleotide (FMN).
15. Write the classification of amino acids with examples. Explain Gabriel Phthalimide
Synthesis and streekers synthesis for the preparation of amino acids.
Or
16. Write the general nature of protein discuss the primary and secondary structure of
proteins?
———————