Exam Details

Subject imsc - ph.d - in biotechnology
Paper
Exam / Course ima/imsc
Department
Organization central university
Position
Exam Date 2017
City, State telangana, hyderabad


Question Paper

1. Which of the following is correct according to boiling point of the compounds?

HF >HCl>H20 NH3

HF H20 NH3

H20> HF NH3

H20> HF NH3>HCl

2. 250 J of heat is required to increase the temperature of an ideal gas by 10 K at constant pressure. If the same gas is heated at constant volume, the amount of heat required to increase the temperature by 10K will be

126J

167 J

250J

333 J

3. The number of electrons in the outer orbital of semiconductors will be

Two

Four

Eight

Any of the above

4. Which of the following the equation represents the line with a y-intercept of 70 and a slope of l5?

Y=15x +70

X=70y +15

Y=70x +15

X=15y 70

5. What is the simple interest earned on Rs.50,000 invested for 6 months at a rate of per annum?

Rs.2,500

RS.750

Rs.1,250

Rs.625

6. The sides of a rectangle are in the ratio of 4:3 and its area is 108 cm^2. The perimeter of the rectangle in cm is









7. Which one of the following statements is correct?

Cellulose is a homopolymer of glucose

Insulin is a heteropolymer of glycine and tryptophan

Lactose consists of glucose and fructose

Maltose consists of galactose and glucose

8. Which one of the following breaks an ester bond?

Lipase

Hexokinase

Polymerase

Helicase

9. In the isolation of DNA, removal of protein and RNA is carried out by enzymes and respectively

Protease and cellulose

Lysozyme and ribonuclease

Protease and ribonuclease

Ribonuclease and chitinase

10. Highest electropositive element is

Cs

Fe

Au

Fr

11. MgO composed of

Covalent bond

Ionic bond

Metallic bond

Coordinated covalent bond

12. The number of moles of solute present in 600 ml of 0.05 M solution is

0.003

0.03

0.30

3.0

13. Absorption of dye solution on a blotting paper is due to

Viscosity of the dye

Diffusion of the dye

Capillary force

All the above

14. Area of a circle of radius 5 cm is .... Sqcm

3.14X5

3.14X5X5

3.14X5X5X5

14X 2X 5

15. Raju and Ramu own two pieces of adjacent lands. The area of both the lands together in square meters is three times the area of Ramu and is 750 square meters. What is the area ofRaju's land?

500 square meters

450 square meters

300 square meters

750 square meters

16. Which of the following molecules does not have a net dipole moment?

H20

NH3

BF3

BrF5

17. Atoms that have same number of protons but different number of neutrons are called

Isotope

Isobar

Isotone

Isomer

18. The orthocenter of the triangle formed by is









19. Which term of the AP: .... is

10th

12th

9th

8th

20. Which one of the following values will be positive?

sin

cosine

cos

tan

21. If circle represents guitarists, square represents singers and triangle represents dancers, the number of people who can sing and dance, but cannot play guitar are

<img src='./qimages/15975-21.jpg'>

Five

Three

Two

One

22. If a person standing on stationary boat throws a ball of 0.5 kg which travels with a speed of 10 what will be the speed of boat's movement after throwing the ball? Consider that the weight of the person and boat is 50 kg each and friction between the lake water and boat is insignificant.

(a)0.05 m/s

0.10 m/s

0.20 m/s

(d)0.50 m/s

23. A light of wavelength traveling in air is 480 nm which incidents on glass having refractive index of 1.5. The wavelength of light inside the glass will

320 nm

480 nm

560 nm

720 nm

24. The capacitance of a capacitor storing 0.5 C at 10 V is

20F

10F

0.1F

0.05F

25. Bronze is an alloy of

Copper and silver

Copper and mercury

Copper and tin

Copper and iron

26. Glyceraldehyde-3-phosphate is an isomer of

Fructose-6-phosphate

Dihydroxy acetone phosphate

Glucose-6-phosphate

Glycerol-3-phosphate

27. Codon bias and CpG islands are useful in eukaryotic genome to

Find the DNA binding domains

Identify gene function

Identify open reading frame

Identify repeats in DNA

28. The dye used to track the migration of proteins in the polyacrylamide gel electrophoresis

Xylene cyanol

B-mercaptoethanol

Bromophenol blue

Coomassie brilliant blue

29. Which technique can be used to detect the protein-protein interaction?

Co-immunoprecipation

Yeast-two hybrid system

FRET Microarray

All the above

30. 'Transversion' is a type of

Chromosomal aberration

Point mutation

Suppressor mutation

None of the above tryptophan?

31. Which of the following methods could be most readily employed to identify

Electrophoresis

Ultraviolet spectroscopy

Gel filtration chromatography

Analytical ultracentrifugation

32. Which vitamin is produced by the microorganisms present in normal microbiota?

Vitamin A

Vitamin C

Vitamin D

Vitamin K

33. In cation exchange chromatography, the solid support should be

Neutral

Zwitterion

Positively charged

Negatively charged

34. The term 'hyperglycemia' refers to

Increased blood sugar

Decreased blood sugar

Inhibits the process of gluconeogenesis

Stimulation of cellular glucose uptake by glucagon

35. Chemically'Agar' belongs to one of the following macromolecules

Nucleic acids

Proteins

Carbohydrates

Lipids

36. Which of the following set of amino acids consists of only apolar/hydrophobic side chains?

Ala, Leu, He, Phe

Ser, Gly, Pro, Leu

Gly, Lys, Asn, Arg

Ser, Glu, Asp, Thr

37. The chromatography in which the ligand is immobilized to the column matrix is

Gel Filtration

Affinity

Ion exchange

Hydrophobic

38. The compound which cannot be metabolized to pyruvate is

Alanine

Cysteine

Serine

Phenylalanine

39. STRING is a database of

Protein sequences

Protein structures

Protein-Protein interaction networks

DNA sequences

40. The immunoglobulin that results in the histamine release is

IgG

IgM

IgE

IgD

41. The slope Km/Vmax indicate

Competitive inhibition

Un-Competitive inhibition

Non-Competitive inhibition

Allosteric Inhibition

42. Gene bank is a nucleic acid sequence database which is maintained by

DNA database Japan

National Centre for Biotechnology Information (NCBI)

European Molecular Biology Laboratory

Sanger Institute

43. Characteristic feature of allosteric protein is

Kcat is very high

Cooperativity

Aggregation

Helix-coil transition

44. has very restricted conformational freedom

Pro

Gly

His

Trp

45. Hoogstein hydrogen bonding is present in

Z-DNA

RNA

Triplex DNA

B-DNA

46. If a heterogenous offspring is crossed with homogenous recessive parent, such activity is called

Back cross

Reciprocal cross

Test cross

Dihybrid cross

47. Aneuploidy refers to

2n

2n+l

4n

4n+1

48. Following is associated with breast cancer

BRCAI

BRCA2

Both

Neither

49. SOS response involves

Thymidine dimer formation

DNA strand breaks

Lex A cleavage

All the above

50. Hydrogen bond is formed between

An uncharged hydrogen atom with an uncharged atom

A partially positively charged hydrogen atom with a partially negatively charged electronegative atom

A partially positively charged hydrogen atom with an uncharged electronegative atom

An uncharged hydrogen atom with a partially negatively charged electronegative atom

51. The severely affected people who possesses most common form having more than 1000 repeats of the CTG triplet is

Myotonic dystrophy

Fragile X syndrome

Retinoblastoma

None of the above

52. Protein surface is predominantly comprises of amino acid residues

Polar

Apolar/hydrophobic

Neutral

Charged

53. In an ideal a-helix every carbonyl oxygen of an amino acid residue "i" is hydrogen bonded to an amide hydrogen of amino acid residue" "

i+l

i+2

i+3

i+4

54. Which of the following statements concerning proteins is CORRECT?

Alpha helices are stabilized by hydrogen bonding between the carbonyl oxygen and the amide hydrogen of amino acids.

Proteins are the only molecules that can catalyze reactions in the cell.

The peptide bond is formed through a hydrolysis reaction.

Disulfide bonds are formed from ionic interactions between charged amino acids.

55. Which statement about mitochondrial genomes is FALSE?

They use a genetic code different from the standard eukaryotic genetic code.

Their genes do NOT have introns.

They probably arose as a result of a symbiotic event with formerly free living organisms.

They contain genes necessary for all mitochondrial functions.

56. Which of the following has the highest percentage of modified bases?

hnRNA

(b)mRNA

rRNA

tRNA

57. Which of the following enzymes in the anabolic pathway given below is most likely to catalyze the rate limiting step in the biosynthesis of A6?

EE L A. j E.,

E1

E2

E3

Es

58. Which one is a common compound shared by the TCA cycle and the urea cycle?

a-keto glutarate

Argino succinic acid

Fumarate

Aspartic acid

59. Which of the following statements best describe an allosteric binding site?

It is a binding site containing amino acids with aliphatic side chains.

It is a binding site that can accept a wide variety of differently shaped molecules.

It is a binding site, which is separate from the active site, and affects the activity of an enzyme when it is occupied by a ligand.

It is a description of an active site which has undergone an induced fit.

60. BCG vaccine is used for

TB

Cholera

Plague

Influenza

61. Chemical mediated introduction of DNA into a bacterial cell termed as

Transformation

Transcription

Transduction

Conjugation

62. The antibiotic that does not bind to the ribosome is

Streptomycin

Tetracycline

Erythromycin

Penicillin

63. Monoclonal antibodies are against

Single antigen

Single epitope

Single paratope

Single antibody

64. The cell wall ofthe following is not rigid in

Fungus

Archaea

Protozoa

Bacteria

65. The amino acid that shows characteristic absorbance at 280 nm is

Methionine

Lysine

Valine

Tryptophan

66. The codon UAA codes for

Methionine

Threonine

Tryptophan

Termination

67. 'Toxemia'means

A disease caused by toxins

Circulation of toxins in the blood

Secretion of toxins by microbes

Inactivation of toxins

68. Collagen has

Single helical structure

Double helical structure

Triple helical structure

No defined structure and is disordered

69. Rapid but non-antigen specific immune responses are produced by the

Adaptive immune response

Innate immune system

Leukocytes

Lymphatic system

70. Deficiency of thymus results in increased infections in humans, such a condition is called

Thymectomy

Graves disease

DiGeorges syndrome

All the above

71. In Krebs cycle two moles of glucose produces

1 mole of ATP

2 moles of ATP

4 moles of ATP

8 moles of ATP

72. A 'bioreactor' is a

Analyzer

Fermenter

Radiator

Coolater

73. Prokaryotic translation elongation factor G its activity

(a)GTP

(b)ATP

(c)CTP

(d)UTP

74. Viroids consists of

Only proteins

Only envelops

Only capsids

Only nucleic acids

75. During the bacterial growth, the primary metabolites will be produced during

Lag phase

Log phase

Stationary phase

Decline phase


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