1. Half life of adenosine is

10 sec

100 sec

60 sec

16 sec

2. Diabetes Mellitus is characterized by

Polyuria

Thirst

Weight loss

All of the above

3. HELLP syndrome includes all of the following except:

High platelet count

Elevated liver enzymes

Haemolysis

Low platelet count

4. Ankle -Brachial Index is a tool for the diagnosis of

Body mass index

Varicose veins

Co arctation of Aorta

Peripheral arterial disease

5. Ketone bodies are all except

Acetone

Glucose

Acetoacetate

Beta hydroxyl buterate

6. Amiodarone is contraindicated in pregnancy due to

Bradycardia in mother

QT prolongation in foetus

Foetal hypothyroidism

All of the above

7. Eclampsia is characterized by all except

Hypertension

Seizures

Hyperglycaemia

Proteinuria

8. HbA1c indicates the glycaemic status of the past .

4 months

2 months

3 months

1 year

9. Which of the following is not a microvascular complication of diabetes?

Ischemic Cardiomyopathy

Retinopathy

Nephropathy .

Neuropathy

10. Which of the following antihypertensive is safest used during pregnancy?

Telmisartan

Propranolol

Torsemide

Cilnidipine

11. All of the following increase during pregnancy except:

Systemic vascular resistance

Blood volume

Stroke volume

Heart rate

12. Potentially life threatening acute complication of Metformin is

Lache acidosis

Renal failure

Flatulence

Hypoglycaemia

13. Slq3t3 is sign of

Myocardial infarction

Pulmonary embolism

Lbbb

None of the above

14. Least common source of pulmonary embolism is:

Amniotic fluid embolism

Calf vein thrombi

Large veins of the legs

Cardiothoracic surgery

15. Most definitive method for diagnosing Pulmonary Embolism:

Pulmonary angiography

q scan

ECG

Doppler study

16. Third generation sulfonylurea is

Glimiperide

Tolbutamide

Glipizide

Gliclazide

17. False about Acarbose is

Relatively weak anti diabetic

Chances of hypoglycaemia are less

It is relatively cheap

It can't be used in renal failure

18. Absolute deficiency of insulin results in

NIDDM

IDDM

MODY

All of the above

19. MODY is a subset of

Type I DM

Type II DM

Both

None

20. Obesity and diabetes are closely related.

Type I

Type II

Type III

Type IV

21. Goals of diabetes treatment are all except:

HbA1c

FBS 126 mg/dl

PPBS 200

Use Insulin than OHAs

22. Pioglitazone was withdrawn due to

Hepato -toxicity

Renal toxicity

Bone toxicity

Thyroid toxicity

23. Diet control is the in Glycaemia control.

First step

Second step

Third step

Fourth step

24. Short acting insulin is

Regular insulin

Lente insulin

Biphasic insulin

Glargine insulin

25. Which of the following is not an Oral Hypoglycaemic drug?

Saxagliptin

Voglibose

Glimipreide

Indomethacin

26. Deficiency of hormone causes Diabetes.

Glucagon

Insulin

Thyroxin

Cortisol

27. Diagnosis of Non Ketotic Hyperosmolar coma is done by all of the following except:

Blood pH 7.3

Absence of ketones

Serum bicarbonate> 20 mEqjL

All of the above are diagnostic

28. High levels of blood sugars over a long period of time results in and of lipoproteins.

Oxidation and reduction

Reduction and glycosylation

Oxidation and glycosylation

Addition and subtraction

29. Which of the following is not a macrovascular complication of diabetes?

Hypertension

Retinopathy

Dyslipidaemia

Cerebro vascular disease

30. Which of the following is not a characteristic of Neuropathic foot?

Warm

Foot pulses palpable

Foot pulses impalpable

Veins on dorsum of foot distended

31. Hammer toe deformity is seen in:

Neuropathic foot

Pregnancy

Down's syndrome

Patau's syndrome

32. Cilostazol is found to be useful in patients suffering from:

Diabetic nephropathy

Diabetic retinopathy

Diabetic foot

Ischaemic cardiomypathy

33. Hallmark of endothelial changes occurring in capillaries of Diabetic patients is

Thinning of the basement membrane

Sequestration of the basement membrane

Ulceration of basement membrane

Thickening of basement membrane

34. Metabolism of glucose when glucose levels are very high is by

Sorbitol pathway

Ergoterol pathway

Alcohol pathway

Amazon pathway

35. Diabetic maculopathy is a stage seen in

Diabetic nephropathy

Diabetic neuropathy

Diabetic foot

Diabetic retinopathy

36. Cotton wool spots in Diabetic retinopathy indicate:

Focal hyperaemia

Focal ischaemia

Focal proliferation

Focal haemorrhage

37. Cataracts in diabetics:

Occur early and progress rapidly

Occur early and progress slowly

Occur late and progress rapidly

Occur late and progress slowly

38. Diabetic mononeuropathy affecting the ocular muscles is

Permanent

Lasts only 2-6 months and is reversible

Lasts> 1 year and is not reversible

Lasts> 5 years and may be reversible

39. Laser photocoagulation is done in

Exudative maculopathy

Proliferative retinopathy

Both

None

40. The following are the symptoms of Autonomic Neuropathy:

Gustatory sweating

Focal loss of sweating

Hypoglycaemia unawares

All of the above

41. The commonest vessels involved in Diabetics which cause Lacunar Infarcts are:

Small penetrating vessels of the brain and brain stem

Large penetrating vessels

Medium penetrating vessels

None of the above

42. Complications of ischemic foot are all except:

Caludication

Painful ulceration

Painless ulceration

Rest pain

43. ACE Inhibitors preferentially dilate the

Afferent

Efferent

Both

ACE Inhibitors have independent action regardless of the arterioles

44. In Asthmatics with diabetes and IHD, to manage tachycardia, you may use with ACE Inhibitors.

Metoprolol

Nifedipine

Amlodipine

Atenolol

45. A diabetic patient is more prone for renal injury from:

NSAIDs

Contrast agents

Aminoglycosides

All of the above

46. According to broca's formula, the minimum amount of calories needed for basal metabolic activities is Kcal/kg body weight.

11

22

33

44

47. Sweetening agents available are all except:

Saccharin

Aspartame

Acetone

Acesulfame

48. Insulin secretagogues are all except:

Glipizide

Glimiperide

Tolbutamide

Spiromide

49. Glimiperide is a generation sulphonylurea.

1St

2nd

3rd

4th

50. The most easily available Insulin nowadays is

Porcine insulin

Bovine insulin

Genetically engineered insulin

Autologous insulin

51. True about Urogenital Syndrome in diabetics is

Causes painful retention of urine

It results in relatively small residual post voiding urine

Ultimately the bladder becomes more contractile leading to retention

When the intravesical pressure increases more than the pressure of the internal sphincter, overflow incontinence occurs

52. At each visit for a diabetic patient, all of the following has to be checked except:

Weight

HbA1c

FBS and PPBS

ECG

53. The following may not be done annually in diabetic patients to detect chronic complications

ECG

Eye Check -up

USG abdomen

Feeling of distal pulses

54. True about diabetes in pregnancy is

On the day of delivery, the insulin requirement will fall dramatically to preconception levels

There is a progressive drop in insulin requirement till 34 -36 weeks

Control becomes easier as the risk of spontaneous abortion increases in 2nd trimester

During 1St trimester, due to frequent vomiting, the insulin requirement may increase

55. During pregnancy, the rise in blood volume ranges from 20-100% with an average of

25%

50%

75

60%

56. Cardiac output reaches plateau at of pregnancy.

20th week

24th week

28th week

32nd week

57. The blood pressure response during pregnancy is the following except:

BP starts to fall during pt trimester

Maximum fall is in l11.id pregnancy

BP returns to pre gestational levels before term

Reduction in systemic vascular resistance due to reduced vascular tone is responsible for the rise in BP during pregnancy

58. Supine Hypotension Syndrome of Pregnancy occurs with significant fall in heart rate and BP in of patients.

11

22

33

44%

59. Cervical venous hum during pregnancy is heard in

Right supra clavicular fossa

Left supra clavicular fossa

Lower left sterna border

Epigastric region

60. X-ray and pregnancy, true statement is

Since the radiation dose during routine X-·ray is minimal, the potential for adverse biological effects from any amount of exposure to radiation during pregnancy must not be avoided

Even though ECHO is available, X-ray still remains the most favourable investigation of choice in pregnancy

The abdomen and pelvis need to be covered with lead material while taking X-ray in a pregnant woman

Exposure during 10-50 days of gestation does not cause teratogenic effect

61. Foeto -placental unit, false is

Unbound free drug only can pass through the placental barrier

Non ionized lipid soluble molecules can cross placenta than less lipid soluble ones

Maternal and foetal pH influences the crossing the placenta

All the above are true

62. Pregnancy and drug metabolism, false is

The affinity of the drug to bind to foetal plasma proteins may be different from that of maternal proteins

Most of the drugs are primarily excreted by diffusion back into the maternal compartment

Congenital malformations are generally caused due to drug toxicity occurring during 3rd trimester

All are true

63. Progesterone causes in intestinal mOtility.

Increase

Decrease

Has no effect

Progesterone causes hypermotiHty

64. Following is not a class IE antiarrythmic

mexiletine

procainamide

phenytoin

lidocaine

65. Drugs that reduce the rate of rise of action potential, primarily slow conduction and can prolong refractoriness minimally are all except:

Flecainide

Propafenone

Moricizine

Spiromide

66. Amiodarone, true is

High amounts in breast milk

Safe in nursing mothers

Causes Uro developmental problems in foetus

Low iodine content

67. Regarding safety in pregnancy, the following are categorized into Category B except:

Oral Ampicillin

Nystatin vaginal preparation

Parenteral cephalosporins

Oral nitrofurantoin

68. Furosemide in pregnancy, false is

Also used to treat pulmonary oedema associated with pre ecclampsia

Usual dose is initial 10 mg i.v

There is no fixed dose for its use

All are true

69. True about spironolactone:

Anti aldosterone agent

Used to treat angina

Shows increasing mortality in severe heart failure patients

Very safe in pregnancy

70. The following are thiazide diuretics;

Hydrochlorthiazide

Chlorthiazide

Chlorthalidone

All of the above

71. According to 0 Sullivan criteria for diagnosis of gestational diabetes, the glucose value at 1 hour should exceed

190 mg

100 mg

240 mg

300 mg

72. Impaired glucose tolerance in pregnancy is when the post prandial value is less than mgs while the fasting blood glucose levels is in between 110-125 mgs.

140

120

160

190

73. Pre ecclampsia IS proteinuria with hypertension occurring after weeks of gestation:

12 weeks

weeks

24 weeks

30 weeks

74. Which of the following is not an Phosphodiesterase 'Type III inhibitor

Amrinone

Milrinone

Ves:1arinone

Furosemide

75. Which of the following is not an AdrenergiC agonists

Dobutamine

Dopamine

Nor adrenaline

All are adrenergic agonists

76. Which of the following drugs can cause foetal cyanide poisoning if used for more than 4 hours as infusion

Hydralazine

Labetalol

Nifedipine

Sodium nih'o prusside

77. Lifestyle modifications during pregnancy with hypertension includes all except:

Quit tobacco consumption

Restrict sodium intake to 5g

Avoid alcohol

All the above are advised

78. Which of the following features differentiates chronic hypertension from pre-ecclampsia

Primigravida patient

Rare occurrence of LVH

Presence of proteinuria

More common in older patients more than 30 years of age

79. Ventricular tachycardia is in pregnancy.

Rare

Very common

Never occurs

When it occurs, it is seen in patients with structurally normal heart

80. Drug of choice for Idiopathic right ventricular outflow tract tachycardia is

Alpha blocker

Beta blocker

Calcium channel blocker

Ace Inhibitor

81. Non synchronized shock is delivered in

Ventricular tachycardia

Ventricular fibrillation

Supraventricular tC1chycardia

Complete heart block

82. True about pulmonary hypertension in pregnancy are all except:

Loud S2

Cyanosis is an early feature

Systolic murmur in pulmonary area

Systolic pulsation of dilated pulmonary artery in 2nd left pulmonary artery

83. The following are the common clinical presentations of Pulmonary Embolism except:

Acute unexplained dyspnoea

Acute right ventricular failure

Pulomanry infarction or haemorrhage

Acute pain abdomen

84. Clinical signs which should lead to search for pulmonary embolism except:

Unexplained sinus tachycardia or techypnoea

Fever, crepitations, pleural rub

Hypertension

Hypotension

85. Which of the following is a pre disposing factor for venous thromboembolism?

Long distance air travel

Coronary angioplasty

Echocardiogram testing

Ventricular tachycardia

86. Causes for Pulmonary Embolism are all except:

Venous thromboembolism

Right sided infective endocarditis

Right atrial myxoma

All of the above

87. A patient who develops PAH without evidence for heart, lung or respiratory disease as a contributory cause is called as

Primary pulmonary hypertension

Secondary pulmonary hypertension

Eisenmenger's complex

Cyanotic heart disease

88. With respect to blood clotting, pregnancy is a state.

Hypocoagulable state

Hypercoagulable state

Both hypercoagulable and hypocoagulable state

Pregnancy has no effect on coagulability

89. LMWH. All of the following are true except:

It is an attractive alternative drug in pregnant women with prosthetic valves.

It crosses placenta

Low incidence of heparin induced thrombocytopaenia

Sustained anticoagulant effect

90. All are causes for Cor Pulmonale except:

Chronic bronchitis

Bullous emphysema

Bronchial asthma

Low altitude dwellers