FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
RESPIRATORY DISEASES
PAPER I

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
Time 3 hours RPD/D/17/D/42/I
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Structure of surfactant proteins.
Functions of surfactant proteins.
Regulation of surfactant production.

2. Oxygen dissociation curve.
Alteration of oxygen affinity.
Bohr Effect.

3. Diffusion capacity of carbon monoxide (DLCO).
Factors influencing diffusion capacity.
5+5
4. Respiratory contribution to acid-base balance.
Base excess and base deficit
Hyperchloraemic acidosis.

5. Morphology of emphysema.
Risk factors for COPD.
5+5
6. Cells of the immune system in asthma.
Molecular mediators in asthma.
5+5
7. Aerosol delivery during invasive mechanical
ventilation.
Pulmonary toxicities associated with anti-rheumatic
and anti-inflammatory drugs.
5+5
8. Physiologic changes in respiratory system in
pregnancy.
Sleep disordered breathing and pregnancy.
6+4
9. Clinical and molecular characteristics of lung cancer in
smokers and non smokers.
EGFR mutations in non-small cell lung cancer.
5+5
P.T.O.
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
RESPIRATORY DISEASES
PAPER I

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
10. Research design.
Observational study.
Meta analysis.
Cohort Study.