FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PHARMACOLOGY
PAPER-III
PHARMA/D/17/34/III
Time: 3 hours
Max. Marks:100
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space
• Answer all the parts of a single question together.
• Start the question to a question on a fresh page or leave adequate space between
two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Chi Square test and its application in
pharmacological research
Principle and method of determinants of sample
size calculations for clinical trials
5+5
2. Current strategies to overcome antimicrobial
resistance
Pharmacotherapy of osteoporosis
5+5
3. Mention targeted cancer therapies giving
examples.
Mechanism of action and potential uses of
bevacizumab.
5+5
4. Enumerate current drugs used for leishmaniasis
with their merits and demerits
Mechanism of action and adverse reaction of
miltefosine
5+5
5. Enumerate anti-malarial drugs used as radical
curatives and gametocytocidal
Pharmacotherapy of chloroquine resistant malaria
4+6
6. What are the differences between conventional
and atypical anti-psychotic agents?
Enumerate drugs with their mechanism of action
for cognitive deterioration.
5+5
7. Write the difference between succinylcholine and
d-tubocurarine
Pharmacotherapy of migraine
5+5
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
8. Enumerate various class of drugs used in cardiac
arrhythmias.
Clinical pharmacology, adverse reactions and
therapeutic uses of sotalol
5+5
9. Discuss pharmacotherapy of multi-drug resistant
tuberculosis.
Outline mechanisms and adverse effect of drugs
used in leprosy.
5+5
10. Rational antihypertensive drug combinations.
Role of vasopeptidase inhibitor in cardiac failure.
5+5